Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis

Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis

The hypothalamic-pituitary-thyroid (HPT) axis regulates a wide range of physiological processes. Here the authors show that hypothalamic tanycytes play a role in the homeostatic regulation of the HPT axis; activation of TRH signaling in tanycytes elevates their intracellular Ca2+ via Gαq/11 pathway,...

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Bibliographic Details
Main Authors: Helge Müller-Fielitz, Marcus Stahr, Mareike Bernau, Marius Richter, Sebastian Abele, Victor Krajka, Anika Benzin, Jan Wenzel, Kathrin Kalies, Jens Mittag, Heike Heuer, Stefan Offermanns, Markus Schwaninger
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00604-6

Internet

https://doi.org/10.1038/s41467-017-00604-6

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