Skeletal Response to Insulin in the Naturally Occurring Type 1 Diabetes Mellitus Mouse Model

Skeletal Response to Insulin in the Naturally Occurring Type 1 Diabetes Mellitus Mouse Model

ABSTRACT Patients with type 1 diabetes mellitus (T1DM) exhibit reduced BMD and significant increases in fracture risk. Changes in BMD are attributed to blunted osteoblast activity and inhibited bone remodeling, but these cannot fully explain the impaired bone integrity in T1DM. The goal of this stud...

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Bibliographic Details
Main Authors: Manisha Dixit, Zhongbo Liu, Sher Bahadur Poudel, Gozde Yildirim, Yanjiao Zhang Zhang, Shilpa Mehta, Omer Murik, Geona Altarescu, Yoshifumi Kobayashi, Emi Shimizu, Mitchell B. Schaffler, Shoshana Yakar
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:JBMR Plus
Subjects:
BONE
MICRO‐CT
NOD MICE
OSTEOCYTE
RAMAN SPECTROSCOPY
TYPE 1 DIABETES MELLITUS
Online Access:https://doi.org/10.1002/jbm4.10483

Internet

https://doi.org/10.1002/jbm4.10483

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