SPEN, a new player in primary cilia formation and cell migration in breast cancer

Abstract Background The primary cilium is a microtubule-based and nonmotile organelle functioning as a cellular antenna that is involved in the regulation of cell proliferation, differentiation, and migration. In breast cancer cells, the primary cilium is a structure that decreases in incidence with...

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Bibliographic Details
Main Authors: Stéphanie Légaré, Catherine Chabot, Mark Basik
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Breast Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13058-017-0897-3