Whole-genome cartography of estrogen receptor alpha binding sites.

Whole-genome cartography of estrogen receptor alpha binding sites.

Using a chromatin immunoprecipitation-paired end diTag cloning and sequencing strategy, we mapped estrogen receptor alpha (ERalpha) binding sites in MCF-7 breast cancer cells. We identified 1,234 high confidence binding clusters of which 94% are projected to be bona fide ERalpha binding regions. Onl...

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Bibliographic Details
Main Authors: Chin-Yo Lin, Vinsensius B Vega, Jane S Thomsen, Tao Zhang, Say Li Kong, Min Xie, Kuo Ping Chiu, Leonard Lipovich, Daniel H Barnett, Fabio Stossi, Ailing Yeo, Joshy George, Vladimir A Kuznetsov, Yew Kok Lee, Tze Howe Charn, Nallasivam Palanisamy, Lance D Miller, Edwin Cheung, Benita S Katzenellenbogen, Yijun Ruan, Guillaume Bourque, Chia-Lin Wei, Edison T Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1885282?pdf=render

Internet

http://europepmc.org/articles/PMC1885282?pdf=render

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