Reduced CCR6+IL-17A+Treg Cells in Blood and CCR6-Dependent Accumulation of IL-17A+Treg Cells in Lungs of Patients With Allergic Asthma

Reduced CCR6+IL-17A+Treg Cells in Blood and CCR6-Dependent Accumulation of IL-17A+Treg Cells in Lungs of Patients With Allergic Asthma

Human regulatory T (Treg) cells play a central role in controlling allergic inflammation in the airways. A reduced number of peripheral Treg cells and decreased suppressive function have been previously reported in the pathogenesis of allergic asthma. However, the characteristic role of specific Tre...

Full description

Bibliographic Details
Main Authors: Xiaokun Shen, Huiyun Zhang, Hua Xie, Liping Chen, Shinan Li, Junjuan Zheng, Ruonan Chai, Zhao Wang, Yanyan Zang, Shaoheng He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
asthma
HDM
CCR6+ Treg
IL-17
CCL20
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.710750/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.710750/full

Similar Items