The macrophage cytoskeleton acts as a contact sensor upon interaction with Entamoeba histolytica to trigger IL-1β secretion.

Entamoeba histolytica (Eh) is the causative agent of amebiasis, one of the major causes of dysentery-related morbidity worldwide. Recent studies have underlined the importance of the intercellular junction between Eh and host cells as a determinant in the pathogenesis of amebiasis. Despite the fact...

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Bibliographic Details
Main Authors: Joëlle St-Pierre, France Moreau, Steve Cornick, Jeanie Quach, Sharmin Begum, Luz Aracely Fernandez, Hayley Gorman, Kris Chadee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5587335?pdf=render