Elastic free energy drives the shape of prevascular solid tumors.

It is well established that the mechanical environment influences cell functions in health and disease. Here, we address how the mechanical environment influences tumor growth, in particular, the shape of solid tumors. In an in vitro tumor model, which isolates mechanical interactions between cancer...

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Bibliographic Details
Main Authors: K L Mills, Ralf Kemkemer, Shiva Rudraraju, Krishna Garikipati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4114546?pdf=render