Mutational Mtc6p attenuates autophagy and improves secretory expression of heterologous proteins in Kluyveromyces marxianus

Mutational Mtc6p attenuates autophagy and improves secretory expression of heterologous proteins in Kluyveromyces marxianus

Abstract Background The yeast Kluyveromyces marxianus is an emerging cell factory for heterologous protein biosynthesis and its use holds tremendous advantages for multiple applications. However, which genes influence the productivity of desired proteins in K. marxianus has so far been investigated...

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Bibliographic Details
Main Authors: Yang Liu, Wen-Juan Mo, Tian-Fang Shi, Meng-Zhu Wang, Jun-Gang Zhou, Yao Yu, Wen-Shan Yew, Hong Lu
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Microbial Cell Factories
Subjects:
Kluyveromyces marxianus
Heterologous protein expression
Autophagy
MTC6
Ruminal feruloyl esterase
Online Access:http://link.springer.com/article/10.1186/s12934-018-0993-9

Internet

http://link.springer.com/article/10.1186/s12934-018-0993-9

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