The Monocarboxylate Transporter Inhibitor α-Cyano-4-Hydroxycinnamic Acid Disrupts Rat Lung Branching

The Monocarboxylate Transporter Inhibitor α-Cyano-4-Hydroxycinnamic Acid Disrupts Rat Lung Branching

Background/Aims: The human embryo develops in a hypoxic environment. In this way, cells have to rely on the glycolytic pathway for energy supply, leading to an intracellular accumulation of monocarboxylates such as lactate and pyruvate. These acids have an important role in cell metabolism and their...

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Bibliographic Details
Main Authors: Sara Granja, Filipa Morais-Santos, Vera Miranda-Gonçalves, Manuel Viana-Ferreira, Rosete Nogueira, Cristina Nogueira-Silva, Jorge Correia-Pinto, Fátima Baltazar
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Monocarboxylate transporters
Lung morphogenesis
Cell metabolism
Embryo development
Online Access:http://www.karger.com/Article/FullText/356617

Internet

http://www.karger.com/Article/FullText/356617

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