Recent Advances in Models, Mechanisms, Biomarkers, and Interventions in Cisplatin-Induced Acute Kidney Injury

Recent Advances in Models, Mechanisms, Biomarkers, and Interventions in Cisplatin-Induced Acute Kidney Injury

Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as ovarian, head and neck, and testicular germ cell. A known complication of cisplatin administration is acute kidney injury (AKI). The development of effective tumour interventions with reduced nephrotoxicity relies...

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Bibliographic Details
Main Authors: Sara J. Holditch, Carolyn N. Brown, Andrew M. Lombardi, Khoa N. Nguyen, Charles L. Edelstein
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
cisplatin
acute kidney injury
AKI
apoptosis
inflammation
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/20/12/3011

Internet

https://www.mdpi.com/1422-0067/20/12/3011

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