LineageOT is a unified framework for lineage tracing and trajectory inference

Lineage tracing and snapshots of transcriptional state at the single-cell level are powerful, complementary tools for studying development. Here, the authors propose a mathematical method combining lineage tracing with trajectory inference to improve our understanding of development.

Bibliographic Details
Main Authors: Aden Forrow, Geoffrey Schiebinger
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25133-1