Human leukocyte antigen class II haplotypes affect clinical characteristics and progression of type 1 autoimmune hepatitis in Japan.

Although we earlier demonstrated that the human leukocyte antigen (HLA) DRB1*04:05 allele was associated with susceptibility to autoimmune hepatitis (AIH) in Japan, the precise relationship of HLA haplotype and the role of amino acid alignment with disease susceptibility and progression has not been...

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Bibliographic Details
Main Authors: Takeji Umemura, Yoshihiko Katsuyama, Kaname Yoshizawa, Takefumi Kimura, Satoru Joshita, Michiharu Komatsu, Akihiro Matsumoto, Eiji Tanaka, Masao Ota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4067340?pdf=render