Establishment and Characterization of a Reliable Xenograft Model of Hodgkin Lymphoma Suitable for the Study of Tumor Origin and the Design of New Therapies

Establishment and Characterization of a Reliable Xenograft Model of Hodgkin Lymphoma Suitable for the Study of Tumor Origin and the Design of New Therapies

To identify the cells responsible for the initiation and maintenance of Hodgkin lymphoma (HL) cells, we have characterized a subpopulation of HL cells grown in vitro and in vivo with the aim of establishing a reliable and robust animal model for HL. To validate our model, we challenged the tumor cel...

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Bibliographic Details
Main Authors: Radhia M’kacher, Monika Frenzel, Mustafa Al Jawhari, Steffen Junker, Corina Cuceu, Luc Morat, Anne-Laure Bauchet, Lev Stimmer, Aude Lenain, Nathalie Dechamps, William M. Hempel, Geraldine Pottier, Leonhard Heidingsfelder, Eric Laplagne, Claire Borie, Noufissa Oudrhiri, Dima Jouni, Annelise Bennaceur-Griscelli, Bruno Colicchio, Alain Dieterlen, Theodore Girinsky, Raphael Boisgard, Jean Bourhis, Jacques Bosq, Thomas Mehrling, Eric Jeandidier, Patrice Carde
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Cancers
Subjects:
Hodgkin lymphoma
animal model
CD30−/CD15−
telomere dysfunction
telomerase
EDO-S101
Online Access:https://www.mdpi.com/2072-6694/10/11/414

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https://www.mdpi.com/2072-6694/10/11/414

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