HDL inflammatory index correlates with and predicts severity of organ failure in patients with sepsis and septic shock.

OBJECTIVE:High density lipoprotein (HDL) is important for defense against sepsis but becomes dysfunctional (Dys-HDL) during inflammation. We hypothesize that Dys-HDL correlates with organ dysfunction (sequential organ failure assessment (SOFA) score) early sepsis. METHODS:A prospective cohort study...

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Bibliographic Details
Main Authors: Faheem W Guirgis, Sunita Dodani, Christiaan Leeuwenburgh, Lyle Moldawer, Jennifer Bowman, Colleen Kalynych, Victor Grijalva, Srinivasa T Reddy, Alan E Jones, Frederick A Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6138388?pdf=render