Interleukin-4 alters early phagosome phenotype by modulating class I PI3K dependent lipid remodeling and protein recruitment.

Phagocytosis is a complex process that involves membranelipid remodeling and the attraction and retention of key effector proteins. Phagosome phenotype depends on the type of receptor engaged and can be influenced by extracellular signals. Interleukin 4 (IL-4) is a cytokine that induces the alternat...

Full description

Bibliographic Details
Main Authors: Sandra de Keijzer, Marjolein B M Meddens, Dilek Kilic, Ben Joosten, Inge Reinieren-Beeren, Diane S Lidke, Alessandra Cambi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3143135?pdf=render