How the Wnt signaling pathway protects from neurodegeneration: The Mitochondrial Scenario

Alzheimer´s disease (AD) is the most common neurodegenerative disorder and is characterized by progressive memory loss and cognitive decline. One of the hallmarks of AD is the overproduction of amyloid-beta aggregates that range from the toxic soluble oligomer (Aβo) form to extracellular accumulatio...

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Bibliographic Details
Main Authors: Macarena S. Arrázola, Carmen eSilva-Alvarez, Nibaldo C. Inestrosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Wnt
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00166/full