Increased plasma citrulline in mice marks diet-induced obesity and may predict the development of the metabolic syndrome.

Increased plasma citrulline in mice marks diet-induced obesity and may predict the development of the metabolic syndrome.

In humans, plasma amino acid concentrations of branched-chain amino acids (BCAA) and aromatic amino acids (AAA) increase in states of obesity, insulin resistance and diabetes. We here assessed whether these putative biomarkers can also be identified in two different obesity and diabetic mouse models...

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Bibliographic Details
Main Authors: Manuela Sailer, Christoph Dahlhoff, Pieter Giesbertz, Mena K Eidens, Nicole de Wit, Isabel Rubio-Aliaga, Mark V Boekschoten, Michael Müller, Hannelore Daniel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3653803?pdf=render

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http://europepmc.org/articles/PMC3653803?pdf=render

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