Mechanisms of opening and closing of the bacterial replicative helicase

Mechanisms of opening and closing of the bacterial replicative helicase

Assembly of bacterial ring-shaped hexameric replicative helicases on single-stranded (ss) DNA requires specialized loading factors. However, mechanisms implemented by these factors during opening and closing of the helicase, which enable and restrict access to an internal chamber, are not known. Her...

Full description

Bibliographic Details
Main Authors: Jillian Chase, Andrew Catalano, Alex J Noble, Edward T Eng, Paul DB Olinares, Kelly Molloy, Danaya Pakotiprapha, Martin Samuels, Brian Chait, Amedee des Georges, David Jeruzalmi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-12-01
Series:eLife
Subjects:
DNA replication
DnaB replicative helicase
helicase loader
replication initiation
cryogenic electron microscopy
structural biology
Online Access:https://elifesciences.org/articles/41140

Internet

https://elifesciences.org/articles/41140

Similar Items