Effect of N-acetyl-L-cysteine on lymphocyte apoptosis, lymphocyte viability, TNF-alpha and IL-8 in HIV-infected patients undergoing anti-retroviral treatment

Effect of N-acetyl-L-cysteine on lymphocyte apoptosis, lymphocyte viability, TNF-alpha and IL-8 in HIV-infected patients undergoing anti-retroviral treatment

N-acetyl-L-cysteine (NAC) has been proposed as an additional therapeutic agent for AIDS patients because it reduces human immunodeficiency virus type 1 (HIV-1) replication in stimulated CD4+ lymphocytes, and it ameliorates immunological reactivity. In a randomized, 180-day, double-blind, placebo-con...

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Bibliographic Details
Main Authors: Aricio Treitinger, Celso Spada, Ivete Yoshico Masokawa, Júlio César Vidal Verdi, Mariette Van Der  Sander Silveira, Magali Chaves Luis, Marcellus Reis, Silvia Inês Alejandra Cordova de Pires Ferreira, Dulcinéia Saes Parra Abdalla
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
N-acetylcysteine
apoptosis
viability
HIV
glutathione
TNF-alpha
IL-8
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000500005&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000500005&lng=en&tlng=en

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