The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction

<p>Abstract</p> <p>Background</p> <p>Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are tolerated. The rise in available protein sequences continues to in...

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Bibliographic Details
Main Authors: Jefferson Emily R, Manning Jonathan R, Barton Geoffrey J
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/51