Cyclosporin A Increases Mitochondrial Buffering of Calcium: An Additional Mechanism in Delaying Mitochondrial Permeability Transition Pore Opening

Cyclosporin A Increases Mitochondrial Buffering of Calcium: An Additional Mechanism in Delaying Mitochondrial Permeability Transition Pore Opening

Regulation of mitochondrial free Ca<sup>2+</sup> is critically important for cellular homeostasis. An increase in mitochondrial matrix free Ca<sup>2+</sup> concentration ([Ca<sup>2+</sup>]<sub>m</sub>) predisposes mitochondria to opening of the permeab...

Full description

Bibliographic Details
Main Authors: Jyotsna Mishra, Ariea J. Davani, Gayathri K. Natarajan, Wai-Meng Kwok, David F. Stowe, Amadou K.S. Camara
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
cyclosporin A
mitochondria calcium buffering
mitochondria bioenergetics
mitochondria permeability transition pore
inorganic phosphate
Online Access:https://www.mdpi.com/2073-4409/8/9/1052

Internet

https://www.mdpi.com/2073-4409/8/9/1052

Similar Items