8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions
Oxidative stress and the resulting damage to genomic DNA are inevitable consequences of endogenous physiological processes, and they are amplified by cellular responses to environmental exposures. One of the most frequent reactions of reactive oxygen species with DNA is the oxidation of guanine to p...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-04-01
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Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231717305311 |