Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat.

Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat.

BACKGROUND:Kisspeptin and its G protein-coupled receptor (GPR) 54 are essential for activation of the hypothalamo-pituitary-gonadal axis. In the rat, the kisspeptin neurons critical for gonadotropin secretion are located in the hypothalamic arcuate (ARC) and anteroventral periventricular (AVPV) nucl...

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Bibliographic Details
Main Authors: Xiao-Feng Li, James S Kinsey-Jones, Yewsong Cheng, Alice M I Knox, Yuanshao Lin, Nikoletta A Petrou, Antonia Roseweir, Stafford L Lightman, Stuart R Milligan, Robert P Millar, Kevin T O'Byrne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2789414?pdf=render

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http://europepmc.org/articles/PMC2789414?pdf=render

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