Development of a User-Friendly Pipeline for Mutational Analyses of HIV Using Ultra-Accurate Maximum-Depth Sequencing

Development of a User-Friendly Pipeline for Mutational Analyses of HIV Using Ultra-Accurate Maximum-Depth Sequencing

Human immunodeficiency virus type 2 (HIV-2) accumulates fewer mutations during replication than HIV type 1 (HIV-1). Advanced studies of HIV-2 mutagenesis, however, have historically been confounded by high background error rates in traditional next-generation sequencing techniques. In this study, we...

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Bibliographic Details
Main Authors: Morgan E. Meissner, Emily J. Julik, Jonathan P. Badalamenti, William G. Arndt, Lauren J. Mills, Louis M. Mansky
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
HIV-1
HIV-2
sequencing
human immunodeficiency virus
mutation
sequence analysis
Online Access:https://www.mdpi.com/1999-4915/13/7/1338

Internet

https://www.mdpi.com/1999-4915/13/7/1338

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