Adenyl cyclase activator forskolin protects against Huntington's disease-like neurodegenerative disorders

Adenyl cyclase activator forskolin protects against Huntington's disease-like neurodegenerative disorders

Long term suppression of succinate dehydrogenase by selective inhibitor 3-nitropropionic acid has been used in rodents to model Huntington's disease where mitochondrial dysfunction and oxidative damages are primary pathological hallmarks for neuronal damage. Improvements in learning and memory...

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Bibliographic Details
Main Authors: Sidharth Mehan, Shaba Parveen, Sanjeev Kalra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; Huntington′s disease; mitochondria; adenyl cyclase; forskolin; oxidative stress; basal ganglia; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=2;spage=290;epage=300;aulast=Mehan

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=2;spage=290;epage=300;aulast=Mehan

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