Cyst(e)ine in nutrition formulation promotes colon cancer growth and chemoresistance by activating mTORC1 and scavenging ROS

Cyst(e)ine in nutrition formulation promotes colon cancer growth and chemoresistance by activating mTORC1 and scavenging ROS

Abstract Weight loss and cachexia are common problems in colorectal cancer patients; thus, parenteral and enteral nutrition support play important roles in cancer care. However, the impact of nonessential amino acid components of nutritional intake on cancer progression has not been fully studied. I...

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Bibliographic Details
Main Authors: Jiao Wu, Sai-Ching Jim Yeung, Sicheng Liu, Aiham Qdaisat, Dewei Jiang, Wenli Liu, Zhuo Cheng, Wenjing Liu, Haixia Wang, Lu Li, Zhongmei Zhou, Rong Liu, Chuanyu Yang, Ceshi Chen, Runxiang Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00581-9

Internet

https://doi.org/10.1038/s41392-021-00581-9

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