Linearization of Median Genomes Under the Double-Cut-and-Join-Indel Model

Reconstruction of the median genome consisting of linear chromosomes from three given genomes is known to be intractable. There exist efficient methods for solving a relaxed version of this problem, where the median genome is allowed to have circular chromosomes. We propose a method for construction...

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Bibliographic Details
Main Authors: Pavel Avdeyev, Shuai Jiang, Max A Alekseyev
Format: Article
Language:English
Published: SAGE Publishing 2019-06-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.1177/1176934318820534