TdP Incidence in Methoxamine-Sensitized Rabbit Model Is Reduced With Age but Not Influenced by Hypercholesterolemia

Metabolic syndrome is associated with hypercholesterolemia, cardiac remodeling, and increased susceptibility to ventricular arrhythmias. Effects of diet-induced hypercholesterolemia on susceptibility to torsades de pointes arrhythmias (TdP) together with potential indicators of arrhythmic risk were...

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Main Authors: Lukáš Nalos, Dagmar Jarkovská, Jitka Švíglerová, Annabell Süß, Jakub Záleský, Daniel Rajdl, Milada Krejčová, Jitka Kuncová, Josef Rosenberg, Milan Štengl
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.692921/full