X-Ray Crystal Structure of 10β-Hydroxy-4β,5β-epoxyestr-1-en-3,17-dione and Antitumor Activity of its Congeners

X-Ray Crystal Structure of 10β-Hydroxy-4β,5β-epoxyestr-1-en-3,17-dione and Antitumor Activity of its Congeners

Based on the biological properties of epoxyquinols from natural sources, the title compound was synthesised as a potential antitumor agent. Its molecular structure was partially confirmed by NMR studies. The detailed structure was established by X-ray analysis revealing two symmetry independent mole...

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Bibliographic Details
Main Authors: Bogdan A. Šolaja, Miroslav J. Gašić, Zorica Juranić, Marianne Strümpel, Bela Ribar, Borislava Markov, Agneš Kapor, Dragana R. Milić
Format: Article
Language:English
Published: MDPI AG 1999-11-01
Series:Molecules
Subjects:
Steroids
epoxyquinol
quinol
X-ray crystallography
antitumor activity
Online Access:http://www.mdpi.com/1420-3049/4/12/338/

Internet

http://www.mdpi.com/1420-3049/4/12/338/

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