Iridium-Catalysed ortho-Directed Deuterium Labelling of Aromatic Esters—An Experimental and Theoretical Study on Directing Group Chemoselectivity

Iridium-Catalysed ortho-Directed Deuterium Labelling of Aromatic Esters—An Experimental and Theoretical Study on Directing Group Chemoselectivity

Herein we report a combined experimental and theoretical study on the deuterium labelling of benzoate ester derivatives, utilizing our developed iridium N-heterocyclic carbene/phosphine catalysts. A range of benzoate esters were screened, including derivatives with electron-donating and -withdrawing...

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Bibliographic Details
Main Authors: Jennifer Devlin, William. J. Kerr, David M. Lindsay, Timothy J. D. McCabe, Marc Reid, Tell Tuttle
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Molecules
Subjects:
hydrogen isotope exchange
deuterium
iridium
esters
C–H activation
DFT
Online Access:http://www.mdpi.com/1420-3049/20/7/11676

Internet

http://www.mdpi.com/1420-3049/20/7/11676

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