A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A

A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A

A mass spectrometric method is described for monitoring cerebrosides in the presence of excess concentrations of alkali metal salts. This method has been adapted for use in the assay of arylsulfatase A (ASA) and the cerebroside sulfate activator protein (CSAct or saposin B). Detection of the neutral...

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Bibliographic Details
Main Authors: Andrew J. Norris, Julian P. Whitelegge, Arman Yaghoubian, Jean-Rene Alattia, Gilbert G. Privé, Tatsushi Toyokuni, Hubert Sun, Mai N. Brooks, Luigi Panza, Pamela Matto, Federica Compostella, Natascha Remmel, Ralf Klingenstein, Konrad Sandhoff, Claire Fluharty, Arvan Fluharty, Kym F. Faull
Format: Article
Language:English
Published: Elsevier 2005-10-01
Series:Journal of Lipid Research
Subjects:
saposins A, B, C, and D
electrospray ionization
tandem mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520329163

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http://www.sciencedirect.com/science/article/pii/S0022227520329163

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