Phosphorylation regulating the ratio of intracellular CRY1 protein determines the circadian period
The core circadian oscillator in mammals is composed of transcription/translation feedback loop in which cryptochrome (CRY) proteins play critical roles as repressors of their own gene expression. Although post-translational modifications such as phosphorylation of CRY1, are crucial for circadian rh...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-09-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00159/full |