Methylome of human senescent hematopoietic progenitors

Methylome of human senescent hematopoietic progenitors

Abstract Senescence, a state of permanent cell cycle arrest, can be induced by DNA damage. This process, which was initially described in fibroblasts, is now recognized to occur in stem cells. It has been well characterized in cell lines, but there is currently very limited data available on human s...

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Bibliographic Details
Main Authors: Stephen Capone, Anthony R. Colombo, Benjamin K. Johnson, Tim J. Triche, Giridharan Ramsingh
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Experimental Hematology & Oncology
Subjects:
Senescence
Hematopoietic stem and progenitor cells
Inflammation
Transposable elements
Endogenous retroviruses
Whole genome bisulfite sequencing
Online Access:http://link.springer.com/article/10.1186/s40164-018-0123-8

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http://link.springer.com/article/10.1186/s40164-018-0123-8

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