Morphine modulates hippocampal neurogenesis and contextual memory extinction via miR-34c/Notch1 pathway in male ICR mice

Morphine modulates hippocampal neurogenesis and contextual memory extinction via miR-34c/Notch1 pathway in male ICR mice

The opioid Morphine is known to affect neurogenesis in the hippocampus. Evidence has shown that several microRNAs modulate morphine-induced neurogenesis, and hence morphine-induced contextual memory. This complex network has yet to be elucidated. In this study, we screened for morphine addiction rel...

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Bibliographic Details
Main Authors: Hu JieWei, Cui FuHua, Zhang XiaoDong
Format: Article
Language:English
Published: De Gruyter 2020-02-01
Series:Open Life Sciences
Subjects:
mir-34c
morphine
hippocampal neurogenesis
neural differentiation
contextual memory
Online Access:https://doi.org/10.1515/biol-2020-0006

Internet

https://doi.org/10.1515/biol-2020-0006

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