Systematic development of lectin conjugated microspheres for nose-to-brain delivery of rivastigmine for the treatment of Alzheimer’s disease

The current study focuses on development of nasal mucoadhesive microspheres for nose-to-brain delivery of rivastigmine for Alzheimer treatment. A systematic development was employed for optimization of the formulation and process parameters influential on the quality attributes of the microspheres....

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Bibliographic Details
Main Authors: Yang Gao, Waleed H. Almalki, Obaid Afzal, Sunil K. Panda, Imran Kazmi, Majed Alrobaian, Hanadi A. Katouah, Abdulmalik Saleh Alfawaz Altamimi, Fahad A. Al-Abbasi, Sultan Alshehri, Kriti Soni, Ibrahim Abdel Aziz Ibrahim, Mahfoozur Rahman, Sarwar Beg
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221006119