Interaction between the microbiome and TP53 in human lung cancer

Interaction between the microbiome and TP53 in human lung cancer

Abstract Background Lung cancer is the leading cancer diagnosis worldwide and the number one cause of cancer deaths. Exposure to cigarette smoke, the primary risk factor in lung cancer, reduces epithelial barrier integrity and increases susceptibility to infections. Herein, we hypothesize that somat...

Full description

Bibliographic Details
Main Authors: K. Leigh Greathouse, James R. White, Ashely J. Vargas, Valery V. Bliskovsky, Jessica A. Beck, Natalia von Muhlinen, Eric C. Polley, Elise D. Bowman, Mohammed A. Khan, Ana I. Robles, Tomer Cooks, Bríd M. Ryan, Noah Padgett, Amiran H. Dzutsev, Giorgio Trinchieri, Marbin A. Pineda, Sven Bilke, Paul S. Meltzer, Alexis N. Hokenstad, Tricia M. Stickrod, Marina R. Walther-Antonio, Joshua P. Earl, Joshua C. Mell, Jaroslaw E. Krol, Sergey V. Balashov, Archana S. Bhat, Garth D. Ehrlich, Alex Valm, Clayton Deming, Sean Conlan, Julia Oh, Julie A. Segre, Curtis C. Harris
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Genome Biology
Subjects:
Lung cancer
Microbiome
TP53
Squamous cell carcinoma
Mutation
Online Access:http://link.springer.com/article/10.1186/s13059-018-1501-6

Internet

http://link.springer.com/article/10.1186/s13059-018-1501-6

Similar Items