Increased age and male sex are independently associated with higher frequency of blood–cerebrospinal fluid barrier dysfunction using the albumin quotient

Increased age and male sex are independently associated with higher frequency of blood–cerebrospinal fluid barrier dysfunction using the albumin quotient

Abstract Background The cerebrospinal fluid (CSF)/serum quotient of albumin (QAlb) is the most used biomarker for the evaluation of blood–cerebrospinal fluid barrier (B-CSF-B) permeability. For years QAlb was considered only as an age-related parameter but recently it has also been associated to sex...

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Bibliographic Details
Main Authors: Massimiliano Castellazzi, Andrea Morotti, Carmine Tamborino, Francesca Alessi, Silvy Pilotto, Eleonora Baldi, Luisa M. Caniatti, Alessandro Trentini, Ilaria Casetta, Enrico Granieri, Maura Pugliatti, Enrico Fainardi, Tiziana Bellini
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Fluids and Barriers of the CNS
Subjects:
Quotient of albumin (QAlb)
Sex
Age
Cerebrospinal fluid (CSF) analysis
Blood–cerebrospinal fluid barrier (B-CSF-B)
Online Access:https://doi.org/10.1186/s12987-020-0173-2

Internet

https://doi.org/10.1186/s12987-020-0173-2

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