Expression levels of pvcrt-o and pvmdr-1 are associated with chloroquine resistance and severe Plasmodium vivax malaria in patients of the Brazilian Amazon.

Expression levels of pvcrt-o and pvmdr-1 are associated with chloroquine resistance and severe Plasmodium vivax malaria in patients of the Brazilian Amazon.

Molecular markers associated with the increase of chloroquine resistance and disease severity in Plasmodium vivax are needed. The objective of this study was to evaluate the expression levels of pvcrt-o and pvmdr-1 genes in a group of patients presenting CQRPv and patients who developed severe compl...

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Bibliographic Details
Main Authors: Gisely C Melo, Wuelton M Monteiro, André M Siqueira, Siuhelem R Silva, Belisa M L Magalhães, Aline C C Alencar, Andrea Kuehn, Hernando A del Portillo, Carmen Fernandez-Becerra, Marcus V G Lacerda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4144906?pdf=render

Internet

http://europepmc.org/articles/PMC4144906?pdf=render

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