Swi1Timeless Prevents Repeat Instability at Fission Yeast Telomeres.

Genomic instability associated with DNA replication stress is linked to cancer and genetic pathologies in humans. If not properly regulated, replication stress, such as fork stalling and collapse, can be induced at natural replication impediments present throughout the genome. The fork protection co...

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Bibliographic Details
Main Authors: Mariana C Gadaleta, Mukund M Das, Hideki Tanizawa, Ya-Ting Chang, Ken-ichi Noma, Toru M Nakamura, Eishi Noguchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4798670?pdf=render