Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium

Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium

Intestinal organoids are self-organized 3-dimensional (3D) structures formed by a single layer of polarized epithelial cells. This innovative in vitro model is highly relevant to study physiology of the intestinal epithelium and its role in nutrition and barrier function. However, this model has nev...

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Bibliographic Details
Main Authors: Eloïse Mussard, Cécile Pouzet, Virginie Helies, Géraldine Pascal, Sandra Fourre, Claire Cherbuy, Aude Rubio, Nathalie Vergnolle, Sylvie Combes, Martin Beaumont
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Stem Cell Research
Subjects:
Enteroid
Spheroid
Epithelium
Culture medium
Monolayer
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120302816

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http://www.sciencedirect.com/science/article/pii/S1873506120302816

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