Interferon-β1a protects neurons against mitochondrial toxicity via modulation of STAT1 signaling: Electrophysiological evidence

Interferon-β1a protects neurons against mitochondrial toxicity via modulation of STAT1 signaling: Electrophysiological evidence

Multiple sclerosis, one of the main causes of non-traumatic neurological disability in young adults, is an inflammatory and neurodegenerative disorder of the central nervous system. Although the pathogenesis of neuroaxonal damage occurring during the course of the disease is still largely unknown, t...

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Bibliographic Details
Main Authors: Massimiliano Di Filippo, Alessandro Tozzi, Michela Tantucci, Sara Arcangeli, Davide Chiasserini, Veronica Ghiglieri, Antonio de Iure, Paolo Calabresi
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Neurobiology of Disease
Subjects:
Multiple sclerosis
Neurodegeneration
Inflammation
Mitochondria
Rotenone
Interferon-β1a
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113002817

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http://www.sciencedirect.com/science/article/pii/S0969996113002817

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