Multi-omics of the esophageal microenvironment identifies signatures associated with progression of Barrett’s esophagus

Multi-omics of the esophageal microenvironment identifies signatures associated with progression of Barrett’s esophagus

Abstract Background The enrichment of Gram-negative bacteria of oral origin in the esophageal microbiome has been associated with the development of metaplasia. However, to date, no study has comprehensively assessed the relationships between the esophageal microbiome and the host. Methods Here, we...

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Bibliographic Details
Main Authors: Nandan P. Deshpande, Stephen M. Riordan, Claire J. Gorman, Shaun Nielsen, Tonia L. Russell, Carolina Correa-Ospina, Bentotage S. M. Fernando, Shafagh A. Waters, Natalia Castaño-Rodríguez, Si Ming Man, Nicodemus Tedla, Marc R. Wilkins, Nadeem O. Kaakoush
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Genome Medicine
Subjects:
Esophagus
Metaplasia
Adenocarcinoma
Microbiome
Transcriptome
Campylobacter
Online Access:https://doi.org/10.1186/s13073-021-00951-6

Internet

https://doi.org/10.1186/s13073-021-00951-6

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