p-Coumaric acid ameliorates ethanol–induced kidney injury by inhibiting inflammatory cytokine production and NF–κB signaling in rats

p-Coumaric acid ameliorates ethanol–induced kidney injury by inhibiting inflammatory cytokine production and NF–κB signaling in rats

Objective: To examine the effects of p-coumaric acid on ethanol-induced kidney injury in Swiss Wistar rats. Methods: Ethanol (25% v/v) was used to induce nephrotoxicity in rats. p-Coumaric acid was orally administered at 50, 100, or 200 mg/kg body weight. The levels of oxidative parameters were dete...

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Bibliographic Details
Main Authors: Ramakrishnan Sabitha, Kumari Nishi, Vinoth Prasanna Gunasekaran, Govindhan Annamalai, Balupillai Agilan, Mathan Ganeshan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
p-coumaric acid
apoptosis
alcohol
cytokine
inflammation
nephrotoxicity
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=5;spage=188;epage=195;aulast=Sabitha

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=5;spage=188;epage=195;aulast=Sabitha

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