SabA is the H. pylori hemagglutinin and is polymorphic in binding to sialylated glycans.

Adherence of Helicobacter pylori to inflamed gastric mucosa is dependent on the sialic acid-binding adhesin (SabA) and cognate sialylated/fucosylated glycans on the host cell surface. By in situ hybridization, H. pylori bacteria were observed in close association with erythrocytes in capillaries and...

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Main Authors: Marina Aspholm, Farzad O Olfat, Jenny Nordén, Berit Sondén, Carina Lundberg, Rolf Sjöström, Siiri Altraja, Stefan Odenbreit, Rainer Haas, Torkel Wadström, Lars Engstrand, Cristina Semino-Mora, Hui Liu, André Dubois, Susann Teneberg, Anna Arnqvist, Thomas Borén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1626103?pdf=render