Tracking Functional Tumor Cell Subpopulations of Malignant Glioma by Phasor Fluorescence Lifetime Imaging Microscopy of NADH

Tracking Functional Tumor Cell Subpopulations of Malignant Glioma by Phasor Fluorescence Lifetime Imaging Microscopy of NADH

Intra-tumoral heterogeneity is associated with therapeutic resistance of cancer and there exists a need to non-invasively identify functional tumor subpopulations responsible for tumor recurrence. Reduced nicotinamide adenine dinucleotide (NADH) is a metabolic coenzyme essential in cellular respirat...

Full description

Bibliographic Details
Main Authors: Andrew L. Trinh, Hongtao Chen, Yumay Chen, Yuanjie Hu, Zhenzhi Li, Eric R. Siegel, Mark E. Linskey, Ping H. Wang, Michelle A. Digman, Yi-Hong Zhou
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Cancers
Subjects:
Reduced nicotinamide adenine dinucleotide (NADH)
cellular bioenergetics
malignant glioma
tumor cell subpopulation
fluorescence lifetime imaging microscopy (FLIM)
stem-like tumor-initiating cells
tumor mass cells
intra-tumoral heterogeneity
Online Access:https://www.mdpi.com/2072-6694/9/12/168

Internet

https://www.mdpi.com/2072-6694/9/12/168

Similar Items