Evaluating parents’ decisions about next-generation sequencing for their child in the NC NEXUS (North Carolina Newborn Exome Sequencing for Universal Screening) study: a randomized controlled trial protocol

Evaluating parents’ decisions about next-generation sequencing for their child in the NC NEXUS (North Carolina Newborn Exome Sequencing for Universal Screening) study: a randomized controlled trial protocol

Abstract Background Using next-generation sequencing (NGS) in newborn screening (NBS) could expand the number of genetic conditions detected pre-symptomatically, simultaneously challenging current precedents, raising ethical concerns, and extending the role of parental decision-making in NBS. The NC...

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Bibliographic Details
Main Authors: Laura V. Milko, Christine Rini, Megan A. Lewis, Rita M. Butterfield, Feng-Chang Lin, Ryan S. Paquin, Bradford C. Powell, Myra I. Roche, Katherine J. Souris, Donald B. Bailey, Jonathan S. Berg, Cynthia M. Powell
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Trials
Subjects:
Translational genomics
Sequencing
Newborn screening
Parental decision aid
Randomized trial
Online Access:http://link.springer.com/article/10.1186/s13063-018-2686-4

Internet

http://link.springer.com/article/10.1186/s13063-018-2686-4

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