Characterization of DNA Methylation Patterns and Mining of Epigenetic Markers During Genomic Reprogramming in SCNT Embryos

Somatic cell nuclear transfer (SCNT), also known as somatic cell cloning, is a commonly used technique to study epigenetic reprogramming. Although SCNT has the advantages of being safe and able to obtain pluripotent cells, early developmental arrest happens in most SCNT embryos. Overcoming epigeneti...

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Bibliographic Details
Main Authors: Pengbo Cao, Hanshuang Li, Yongchun Zuo, Buhe Nashun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ZGA
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.570107/full