MicroRNA-218 promotes early chondrogenesis of mesenchymal stem cells and inhibits later chondrocyte maturation

MicroRNA-218 promotes early chondrogenesis of mesenchymal stem cells and inhibits later chondrocyte maturation

Abstract Background MicroRNAs (miRNAs) reportedly participate in the mesenchymal stem cell (MSC) chondrogenic differentiation regulation. We objected to examine how miR-218 regulate chondrogenic differentiation of synovium-derived MSCs (SDSCs) and the maturation of RCJ3.1C5.1 chondrocytes. SDSCs wer...

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Bibliographic Details
Main Authors: Song Chen, Zhenyu Xu, Jiahua Shao, Peiliang Fu, Haishan Wu
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Biotechnology
Subjects:
Articular cartilage
microRNA-218
Mesenchymal stem cells
Chondrogenesis
Chondrocyte maturation
Online Access:http://link.springer.com/article/10.1186/s12896-018-0496-0

Internet

http://link.springer.com/article/10.1186/s12896-018-0496-0

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