Immortalization of Porcine 11β-Hydroxysteroid Dehydrogenase Type 1-Transgenic Liver Cells Using SV40 Large T Antigen

Cortisol is a steroid hormone essential to the maintenance of homeostasis that is released in response to stress and low blood glucose concentration. Cortisol is converted from cortisone by 11β-hydroxysteroid dehydrogenase type 1 (HSD11B1). It has been reported that too much cortisol or overexpressi...

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Bibliographic Details
Main Authors: Hee Young Kang, Young-Kwon Choi, Yeon Ik Jeong, Kyung-Chul Choi, Sang-Hwan Hyun, Woo-Suk Hwang, Eui-Bae Jeung
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
pig
Online Access:https://www.mdpi.com/1422-0067/18/12/2625