High Cell Selectivity and Bactericidal Mechanism of Symmetric Peptides Centered on <span style="font-variant: small-caps">d</span>-Pro–Gly Pairs

High Cell Selectivity and Bactericidal Mechanism of Symmetric Peptides Centered on <span style="font-variant: small-caps">d</span>-Pro–Gly Pairs

Antimicrobial peptides (AMPs) have a unique action mechanism that can help to solve global problems in antibiotic resistance. However, their low therapeutic index and poor stability seriously hamper their development as therapeutic agents. In order to overcome these problems, we designed peptides ba...

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Bibliographic Details
Main Authors: Boyan Jia, Yiming Wang, Ying Zhang, Zi Wang, Xue Wang, Inam Muhammad, Lingcong Kong, Zhihua Pei, Hongxia Ma, Xiuyun Jiang
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
antimicrobial peptides
cell selectivity
stability
mechanism
endotoxin neutralization
Online Access:https://www.mdpi.com/1422-0067/21/3/1140

Internet

https://www.mdpi.com/1422-0067/21/3/1140

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